Description

4-Phosphonomethyl-L-Phenylalanine is a specialized phosphonic acid derivative of the essential amino acid L-phenylalanine. This compound is a critical building block in the synthesis of novel pharmaceuticals and biochemical research tools, particularly for targeting specific enzymatic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of enzyme inhibitors, prodrugs, and advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of enzyme inhibitors and targeted therapeutics.
• Biochemical Research: Used as a substrate analog or inhibitor in enzymatic studies and metabolic pathway analysis.
• Prodrug Development: Serves as a modified amino acid backbone for creating phosphate-based prodrugs with enhanced bioavailability.
• Peptide Synthesis: Incorporation into custom peptides to introduce phosphonate functionality for studying protein-protein interactions.
• Agrochemical Research: Investigated as a potential intermediate for novel plant growth regulators or herbicides.
• Diagnostic Agent Development: Potential use in developing contrast agents or biomarkers for medical imaging.

Basic Information

Product Name	4-Phosphonomethyl-L-Phenylalanine
CAS No.	142434-81-9
Molecular Formula	C10H14NO6P
Molecular Weight	275.20 g/mol
Synonyms	L-4-(Phosphonomethyl)phenylalanine; (2S)-2-Amino-3-[4-(phosphonomethyl)phenyl]propanoic acid; PMP; Fosfonometil-L-fenilalanina; 4-(Phosphonomethyl)-L-phenylalanine; Phenylalanine, 4-(phosphonomethyl)-, L-; L-Phe(4-CH2PO3H2)
EINECS	Contact for details

Quality Control

Our 4-Phosphonomethyl-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.