Description

n-Methyl Mesoporphyrin Ix is a synthetic metalloporphyrin derivative, a key compound in biochemical research and diagnostic development. Its value lies in its specific interaction with heme proteins and enzymes, making it an essential tool for studying metabolic pathways and inhibition mechanisms. This product is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on heme biology, cytochrome P450 studies, and photodynamic therapy research.

Application

• Cytochrome P450 Inhibition Studies: Used as a potent and selective inhibitor to probe the structure and function of various CYP isoforms in drug metabolism research.
• Heme Oxygenase Research: Serves as a competitive substrate analog to investigate the enzymatic mechanism of heme degradation.
• Photodynamic Therapy (PDT) Agent Development: Explored as a potential photosensitizer due to its porphyrin core, which can generate reactive oxygen species upon light activation.
• Diagnostic Reagent Manufacturing: Incorporated into biochemical assays and kits for the detection and quantification of specific enzyme activities in clinical and research settings.
• Biochemical Standard: Acts as a reference standard for the calibration of analytical instruments and the validation of methods in analytical chemistry laboratories.
• Academic Research: Employed in university and institutional labs for fundamental studies on porphyrin chemistry, metalloprotein interactions, and bioinorganic mechanisms.

Basic Information

Product Name	n-Methyl Mesoporphyrin Ix
CAS No.	142234-85-3
Molecular Formula	C₃₄H₃₆N₄O₄
Molecular Weight	564.68 g/mol
Synonyms	N-Methyl Mesoporphyrin IX; NMM; N-Methyl Mesoporphine IX; Mesoporphyrin IX, N-methyl-; N-Methyl-mesoporphyrin; Fe(III) N-Methyl Mesoporphyrin IX (when complexed); Protoporphyrin IX analogue, N-methylated; 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid, N-methyl derivative
EINECS	Contact for details

Quality Control

Our n-Methyl Mesoporphyrin Ix is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.