Description

14-Epiandrographolide is a bioactive diterpenoid lactone, a stereoisomer of the well-known natural compound andrographolide. This compound is valued for its distinct pharmacological profile and serves as a critical reference standard and research chemical in the life sciences. It is primarily sought after by researchers and developers in the pharmaceutical, biotechnology, and nutraceutical sectors for investigating anti-inflammatory, hepatoprotective, and immunomodulatory activities. Our supply ensures high purity and batch-to-batch consistency to support rigorous scientific and commercial applications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of andrographolide and related compounds in drug development and quality control (QC/QA).
• Biomedical Research: Serves as a key intermediate or active ingredient in preclinical studies targeting inflammation, cancer, and metabolic disorders.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the standardization and authentication of herbal extracts, particularly from Andrographis paniculata.
• Nutraceutical Development: Employed in the research and formulation of advanced dietary supplements with targeted health benefits.
• Academic Research: Utilized in universities and research institutes for studying diterpenoid biosynthesis, structure-activity relationships (SAR), and novel biological pathways.
• Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) for the detection of diterpenoids in complex matrices.

Basic Information

Product Name	14-Epiandrographolide
CAS No.	142037-79-4
Molecular Formula	C20H30O5
Molecular Weight	350.45 g/mol
Synonyms	14-Epi-andrographolide; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; (5R,8R,9R,10S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-5-hydroxy-6-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-5H-furan-2-one; Andrographolide epimer; 14-Epimer of Andrographolide
EINECS	Contact for details

Quality Control

Every batch of 14-Epiandrographolide is manufactured and analyzed under strict quality management protocols. Our products undergo rigorous identity, purity, and impurity profile testing using advanced analytical techniques including HPLC, GC, and NMR to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and reliability for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.