Description

Azasetron Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) primarily used in the development and manufacturing of antiemetic medications. This compound is a selective serotonin 5-HT3 receptor antagonist, offering significant value in therapeutic applications targeting nausea and vomiting. It is essential for pharmaceutical manufacturers and research institutions engaged in the development of treatments for chemotherapy-induced and postoperative nausea. Azasetron Hydrochloride CAS NO 141922-90-9 is supplied under stringent quality control to ensure batch-to-batch consistency and reliability for critical pharmaceutical processes.

Application

• Pharmaceutical API Synthesis: Key intermediate in the production of finished antiemetic drug formulations.
• Research & Development: Used in preclinical and clinical studies for new 5-HT3 receptor antagonist therapies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical labs.
• Generic Drug Manufacturing: Critical for producing generic versions of established anti-nausea medications.
• Biochemical Research: Tool compound for studying serotonin receptor pathways and mechanisms of emesis.

Basic Information

Product Name	Azasetron Hydrochloride
CAS No.	141922-90-9
Molecular Formula	C19H23N3O2•HCl
Molecular Weight	361.87 g/mol
Synonyms	Azasetron HCl; Y-25130; (+-)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide Hydrochloride; 6-Chloro-4-methyl-3-oxo-N-(3-quinuclidinyl)-3,4-dihydro-2H-1,4-benzoxazine-8-carboxamide Hydrochloride; 2H-1,4-Benzoxazine-8-carboxamide, 6-chloro-3,4-dihydro-4-methyl-3-oxo-N-(3-quinuclidinyl)-, hydrochloride (1:1); Y 25130; Y25130
EINECS	Contact for details

Quality Control

Our Azasetron Hydrochloride is manufactured and tested under a quality management system. Each batch is subjected to rigorous analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards suitable for pharmaceutical use. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.