Description

1-Ethyl-3-(3-Dimethylaminoethyl)Carbodiimide CAS NO 141650-20-6 is a versatile and highly effective zero-length coupling agent, widely recognized for its role in facilitating amide bond formation between carboxylic acids and amines. Its primary value lies in enabling efficient peptide synthesis, bioconjugation, and the preparation of immunogens without becoming part of the final product structure. This makes it an indispensable reagent for research and development laboratories in the pharmaceutical, biotechnology, and life sciences sectors, where precise and reliable molecular conjugation is critical.

Application

• Peptide Synthesis: A key reagent for activating carboxylic acids in solid-phase and solution-phase peptide coupling reactions.
• Protein Cross-linking & Bioconjugation: Used to conjugate proteins, antibodies, or enzymes with other biomolecules, dyes, or solid supports for assays, diagnostics, and drug delivery systems.
• Immunogen Preparation: Facilitates the covalent attachment of haptens to carrier proteins to produce immunogens for antibody generation.
• Polymer & Material Science: Employed in the modification of polymer surfaces and the synthesis of functionalized materials through carbodiimide-mediated chemistry.
• Carbohydrate Chemistry: Used for the activation of uronic acids and other sugar derivatives for glycosylation or labeling studies.
• Nucleic Acid Research: Applied in the modification and labeling of oligonucleotides for probe development.

Basic Information

Product Name	1-Ethyl-3-(3-Dimethylaminoethyl)Carbodiimide
CAS No.	141650-20-6
Molecular Formula	C8H17N3
Molecular Weight	155.24 g/mol
Synonyms	EDC; EDAC; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide Hydrochloride (common salt form); N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide; N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide; WSC; Water-soluble carbodiimide
EINECS	Contact for details

Quality Control

Our 1-Ethyl-3-(3-Dimethylaminoethyl)Carbodiimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive biochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and efficacy. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	108 - 115 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.