Description

Allopumiliotoxin 325A is a specialized alkaloid compound of significant interest in advanced biochemical research. This compound serves as a critical reference standard and building block for pharmacological studies, particularly in neurobiology and toxicology. It is primarily utilized by research institutions and pharmaceutical R&D departments investigating ion channel modulation and novel therapeutic agents.

Application

• Pharmacological Research: Used as a reference standard in studies of sodium channel activity and neurotoxicity mechanisms.
• Neuroscience Studies: A key tool for investigating the effects of neuroactive alkaloids on synaptic transmission and neuronal excitability.
• Toxicology Profiling: Employed in the identification and characterization of bioactive compounds in natural product extracts.
• Drug Discovery: Serves as a molecular scaffold or a comparative agent in the development of new central nervous system (CNS) targeted pharmaceuticals.
• Analytical Chemistry: Functions as a high-purity calibration standard for chromatographic (HPLC, LC-MS) and spectroscopic analysis methods.
• Biochemical Assays: Utilized in in vitro assays to study receptor-ligand interactions and cellular signaling pathways.

Basic Information

Product Name	Allopumiliotoxin 325A
CAS No.	141643-34-7
Molecular Formula	C19H31NO3
Molecular Weight	321.46 g/mol
Synonyms	Allopumiliotoxin 325A; 3,5-Pyrrolidinedione, 2-(1-azabicyclo[2.2.2]oct-5-yl)-4-hydroxy-1-methyl-, (2R,4R,5S)-; (2R,4R,5S)-2-(1-Azabicyclo[2.2.2]oct-5-yl)-4-hydroxy-1-methyl-3,5-pyrrolidinedione; Pumiliotoxin 325A analog; PTX 325A analog; Dendrobatid toxin analog
EINECS	Contact for details

Quality Control

Our Allopumiliotoxin 325A is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.