Description

D-Myo-Inositol 1,4,5-Triphosphate Tripotassium Salt is a high-purity, biologically active derivative of inositol, serving as a critical second messenger in cellular signal transduction. Its primary value lies in its ability to release intracellular calcium stores, making it an indispensable tool for biochemical and pharmacological research. This compound is essential for researchers and manufacturers in the life sciences, particularly for studying calcium signaling pathways, G-protein coupled receptor (GPCR) function, and drug discovery applications.

Application

• Biochemical Research: A fundamental reagent for studying intracellular calcium mobilization and inositol phosphate signaling cascades in vitro.
• Pharmaceutical Development: Used in high-throughput screening (HTS) assays to identify and characterize novel drug candidates targeting GPCRs and phospholipase C pathways.
• Cell Biology Studies: Employed to investigate the role of IP3 in processes such as muscle contraction, neurotransmitter release, and cell growth regulation.
• Diagnostic Kit Manufacturing: A key component in the production of research-grade assay kits for measuring phospholipase C activity or intracellular calcium flux.
• Enzymology: Serves as a substrate for enzymes like inositol polyphosphate phosphatases and kinases in mechanistic studies.
• Neuroscience Research: Critical for elucidating synaptic transmission and neuronal communication mechanisms dependent on calcium signaling.

Basic Information

Product Name	D-Myo-Inositol 1,4,5-Triphosphate Tripotassium Salt
CAS No.	141611-11-2
Molecular Formula	C6H12O15P3·3K
Molecular Weight	540.27 g/mol
Synonyms	IP3 Tripotassium Salt; D-myo-Inositol 1,4,5-trisphosphate Tripotassium Salt; Inositol 1,4,5-Trisphosphate Tripotassium Salt; 1,4,5-IP3 K+ Salt; Ins(1,4,5)P3 Tripotassium; myo-Inositol 1,4,5-trisphosphate Tripotassium; D-Ins(1,4,5)P3 Tripotassium Salt
EINECS	Contact for details

Quality Control

Our D-Myo-Inositol 1,4,5-Triphosphate Tripotassium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay systems. We adhere to relevant quality guidelines for research chemicals to support reproducible and reliable scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Potassium Content	21.0 - 23.0 %
Biological Activity (Calcium Release Assay)	Conforms
Solubility	Soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.