Description

1,5-Anhydro-L-Glucitol is a stable, non-metabolizable sugar alcohol derivative of glucose. This compound serves as a crucial biochemical reference standard and a versatile building block in pharmaceutical and diagnostic research. It is primarily utilized by researchers and manufacturers in the life sciences, particularly for developing enzymatic assays and diagnostic kits for diabetes monitoring. The material is supplied with full traceability and quality documentation to support rigorous scientific and industrial applications.

Application

• Biochemical Research & Reference Standard: Used as a high-purity analytical standard for method development and validation in chromatographic and spectroscopic analyses.
• Diagnostic Reagent Manufacturing: A key component in the formulation of enzymatic assay kits for the quantitative determination of 1,5-anhydroglucitol in human serum, a biomarker for short-term glycemic control.
• Pharmaceutical Intermediate: Acts as a chiral synthon or precursor in the synthesis of more complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Metabolic Studies: Employed in in vitro and in vivo research to study glucose metabolism, renal tubular function, and diabetes-related pathways.
• Food Science & Analysis: Potential application as a marker or additive in specialized nutritional research and food chemistry analysis.

Basic Information

Product Name	1,5-Anhydro-L-Glucitol
CAS No.	141434-71-1
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	1,5-AG; L-1,5-Anhydroglucitol; 1,5-Anhydro-D-Mannitol; 1-Deoxyglucose; 1,5-Anhydro-D-Glucitol; (3R,4R,5R,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
EINECS	Contact for details

Quality Control

Our 1,5-Anhydro-L-Glucitol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results and methods is provided with every shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.