Description

Troxacitabine is a synthetic nucleoside analog with potent antineoplastic activity. This compound is a critical intermediate and active pharmaceutical ingredient (API) in the research and development of novel chemotherapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on oncology and antiviral drug discovery.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel anticancer and antiviral drug candidates.
• Oncology Drug Discovery: Used as a reference standard and active component in preclinical studies targeting leukemia and solid tumors.
• Biochemical Research: Employed in studies of DNA synthesis inhibition, nucleoside metabolism, and enzyme kinetics.
• Antiviral Agent Development: Investigated for its potential activity against viral replication mechanisms.
• Clinical Trial Material: Sourced as a high-purity active pharmaceutical ingredient (API) for formulation into clinical trial supplies.
• Analytical Standard: Used as a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	Troxacitabine
CAS No.	141196-85-2
Molecular Formula	C9H11FN2O5
Molecular Weight	246.20 g/mol
Synonyms	(-)-2'-Deoxy-2',2'-difluoro-3'-oxacytidine; L-OddC; BCH-4556; Troxatyl; L-(-)-dFdC; L-(-)-2'-Deoxy-2',2'-difluorocytidine; L-(-)-2',2'-Difluoro-2'-deoxycytidine; 1-(2-Deoxy-2,2-difluoro-β-L-erythro-pentofuranosyl)cytosine
EINECS	Contact for details

Quality Control

Our Troxacitabine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing compliance with in-house specifications developed for research and pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.