Description

Fumarylpyruvate is a key biochemical intermediate in the metabolic pathways of aromatic amino acids. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in tyrosine and phenylalanine catabolism. It is primarily utilized by research institutions, diagnostic manufacturers, and companies developing enzyme inhibitors or metabolic disorder treatments. Fumarylpyruvate CAS NO 140866-22-4 is supplied to meet the stringent purity requirements of advanced life science applications.

Application

• Biochemical Research: Critical intermediate for studying the homogenisate pathway and related metabolic disorders.
• Enzyme Substrate: Used as a specific substrate for enzymes like fumarylacetoacetate hydrolase (FAH) in activity assays and kinetic studies.
• Pharmaceutical Development: Serves as a reference standard and starting material in the research of potential therapeutics for conditions like tyrosinemia.
• Diagnostic Reagents: Employed in the formulation of diagnostic kits for measuring enzyme activity in clinical and research settings.
• Metabolic Pathway Analysis: Essential for in vitro studies modeling tyrosine metabolism and identifying metabolic bottlenecks.
• Academic & Industrial R&D: Supports fundamental and applied research in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Fumarylpyruvate
CAS No.	140866-22-4
Molecular Formula	C7H6O6
Molecular Weight	186.12 g/mol
Synonyms	(2E)-4-(2-Carboxy-1-oxoethoxy)-4-oxobut-2-enoic acid; 2-Fumarylpyruvic acid; (E)-2-(3-Carboxyacryloyl)oxyacetic acid; Fumarylpyruvic acid; 4-(2-Carboxyacetyl)-2-butenedioic acid; 2-[(1E)-3-Carboxy-1-propenoyl]oxyacetic acid; 140866-22-4; Fumarylpyruvate
EINECS	Contact for details

Quality Control

Our Fumarylpyruvate is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We employ advanced analytical techniques, including HPLC and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term stability, consider storing under an inert atmosphere or in a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.