Description

Adenosine 3',5'-Cyclic Decylphosphoramidate is a chemically modified cyclic nucleotide analog designed for advanced biochemical research and development. This compound serves as a crucial tool molecule for studying cell signaling pathways, particularly those involving cyclic nucleotide-dependent protein kinases. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery, enzymology studies, and the development of novel therapeutic agents targeting intracellular signaling.

Application

• Biochemical Research: As a potent and selective activator or inhibitor in studies of cyclic nucleotide-dependent protein kinases (PKA, PKG).
• Drug Discovery: A key intermediate or reference standard in the development of novel therapeutics targeting cardiovascular diseases, neurological disorders, and metabolic conditions.
• Enzymology Studies: Used to investigate enzyme kinetics, substrate specificity, and the mechanism of action of phosphodiesterases and other nucleotide-metabolizing enzymes.
• Cell Signaling Pathway Analysis: A valuable probe for modulating and understanding intracellular second messenger cascades in various cell types.
• High-Throughput Screening (HTS): Employed as a control compound or library component in screening assays for identifying new kinase modulators.

Basic Information

Product Name	Adenosine 3',5'-Cyclic Decylphosphoramidate
CAS No.	140686-45-9
Molecular Formula	C20H33N6O7P
Molecular Weight	500.49 g/mol
Synonyms	cAMP Decylphosphoramidate; Cyclic AMP Decylphosphoramidate; Adenosine 3',5'-cyclic monophosphate decylphosphoramidate; 8-(6-Aminohexyl)amino-cAMP; 8-AHA-cAMP; N6-Monobutyryl-cAMP; 2'-O-Monobutyryl-cAMP; 8-(4-Chlorophenylthio)-cAMP
EINECS	Contact for details

Quality Control

Our Adenosine 3',5'-Cyclic Decylphosphoramidate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and determination of residual solvents and water content. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.