Description

1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid belonging to the phosphatidylethanolamine (PE) class. This compound is a critical building block for constructing advanced lipid-based delivery systems and biomimetic membranes due to its defined acyl chain structure. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise, consistent lipid components for applications such as liposomal drug formulation and membrane biophysics studies.

Application

• Liposomal Drug Delivery Systems: A key excipient for formulating stable, long-circulating liposomes for targeted cancer therapies, vaccines, and nucleic acid delivery.
• Biomimetic Membrane Research: Used to create model lipid bilayers (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, permeability, and cellular processes.
• Diagnostic Reagents: Incorporated into lipid nanoparticles and assays for diagnostic imaging and biosensor development.
• Cosmetic Nanotechnology: Serves as a structural component in nanoemulsions and nanocarriers for the encapsulation and delivery of active cosmetic ingredients.
• Cell Culture & Cryopreservation: Can be used as a lipid supplement in specialized cell culture media or as a cryoprotectant agent.
• Bioconjugation & Probe Synthesis: The primary amine on the phosphoethanolamine headgroup provides a site for chemical modification with fluorescent dyes, targeting ligands, or other functional groups.

Basic Information

Item	Details
Product Name	1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	140219-78-9
Molecular Formula	C₄₀H₈₀NO₈P
Molecular Weight	734.03 g/mol
Synonyms	1,2-Diheptadecanoyl-sn-glycero-3-phosphoethanolamine; PE(17:0/17:0); Diphytanoyl Phosphatidylethanolamine (common analog name); 1,2-Di(heptadecanoyl)-sn-glycero-3-phosphoethanolamine; DHEPE; Phosphatidylethanolamine (C17:0); 3-sn-Phosphatidylethanolamine, 1,2-diheptadecanoyl-; 1,2-Diheptadecanoyl Phosphatidylethanolamine
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Diheptadecanoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We ensure compliance with stringent internal specifications suitable for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles—generated via techniques like NMR, HPLC, and MS—is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Phase Transition Temperature (DSC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.