Description

15,16-Dihydroxyoctadeca-9Z,12Z-Dienoic Acid is a dihydroxy derivative of linoleic acid, a key intermediate in the biosynthesis of specialized pro-resolving mediators (SPMs) and other oxylipins. This compound matters for its role as a crucial biochemical precursor in research focused on inflammation resolution, lipid signaling, and metabolic pathways. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for developing novel therapeutic agents and studying lipid biochemistry.

Application

• Biochemical Research: Critical intermediate for studying the lipoxygenase pathways and the biosynthesis of pro-resolving lipid mediators like protectins and resolvins.
• Pharmaceutical Development: Serves as a key starting material or reference standard in the R&D of novel anti-inflammatory and immunomodulatory drugs.
• Reference Standard: Used as a high-purity analytical standard in LC-MS, HPLC, and GC-MS for quantifying related metabolites in biological samples.
• Chemical Synthesis: A versatile chiral building block for the organic synthesis of complex natural products and bioactive lipid analogs.
• Nutraceutical Research: Investigated for its potential metabolic and health benefits as a derivative of essential fatty acids.

Basic Information

Product Name	15,16-Dihydroxyoctadeca-9Z,12Z-Dienoic Acid
CAS No.	140129-22-2
Molecular Formula	C₁₈H₃₂O₄
Molecular Weight	312.44 g/mol
Synonyms	15,16-DiHODE; (9Z,12Z)-15,16-Dihydroxyoctadeca-9,12-dienoic acid; 15,16-Dihydroxy-9Z,12Z-octadecadienoic acid; 15,16-DiHODE (C18); 15,16-Dihydroxylinoleic acid; Linoleic acid, 15,16-dihydroxy-; 15,16-Dihydroxyoctadecadienoic acid
EINECS	Contact for details

Quality Control

Our 15,16-Dihydroxyoctadeca-9Z,12Z-Dienoic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.