Description

Precorrin 6Y is a key intermediate in the biosynthesis of vitamin B12 and related corrinoids. This compound is of significant interest for research and development in synthetic biology, enzymatic studies, and the production of high-value biochemicals. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in metabolic pathway engineering and cofactor synthesis.

Application

• Biochemical Research: Critical intermediate for studying the complex enzymatic pathway of vitamin B12 biosynthesis.
• Enzymology Studies: Used as a substrate to investigate the function and kinetics of enzymes like Precorrin-6Y methyltransferase (CobL).
• Synthetic Biology: A building block in engineered microbial pathways aimed at producing cobalamin (Vitamin B12) or novel corrinoids.
• Pharmaceutical Development: Serves as a reference standard and starting material for the synthesis of vitamin B12 analogs and derivatives.
• Metabolic Engineering: Employed in optimizing fermentation processes for the enhanced microbial production of corrinoids.

Basic Information

Product Name	Precorrin 6Y
CAS No.	139663-55-1
Molecular Formula	C46H64N4O17
Molecular Weight	945.02 g/mol
Synonyms	Precorrin-6Y; 1,5,6,15,16,17-Hexadehydro-15,17-seco-cobyrinic acid a,c-diamide hexamethyl ester; Precorrin 6Y ester; Vitamin B12 biosynthesis intermediate 6Y; 15,17-Seco-cobyrinic acid a,c-diamide hexamethyl ester derivative
EINECS	Contact for details

Quality Control

Our Precorrin 6Y is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in pharmaceutical and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a dry, cool, and well-ventilated area. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.