Description

Cyclobutanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, (1R-Trans)- CAS NO 139561-17-4 is a high-purity, chiral cyclobutane derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex, biologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the specific stereochemistry can influence biological activity and environmental profile.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral template in catalytic systems to induce stereoselectivity in chemical transformations.
• Fine Chemical Production: Serves as a specialized intermediate for synthesizing flavors, fragrances, and other high-value fine chemicals with specific stereochemical requirements.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, including ring-opening and functionalization reactions of strained cyclobutane systems.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or advanced materials with unique structural properties derived from the cyclobutane ring.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, (1R-Trans)-
CAS No.	139561-17-4
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R-trans)-2-Isopropenyl-1-cyclobutanecarboxylic Acid Methyl Ester; Methyl (1R,2S)-2-isopropenylcyclobutane-1-carboxylate; (1R,2S)-2-Isopropenylcyclobutane-1-carboxylic Acid Methyl Ester; (-)-trans-2-Isopropenylcyclobutanecarboxylic Acid Methyl Ester; trans-2-(1-Methylethenyl)cyclobutanecarboxylic Acid Methyl Ester; (1R,2S)-2-(Prop-1-en-2-yl)cyclobutane-1-carboxylate; Chiral Cyclobutane Ester Intermediate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, (1R-Trans)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiles. Certificates of Analysis (COA) detailing identity, assay, and purity are available for every batch upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.