Description

Uridine, 4'-C-Azido-5'-Deoxy-5'-Iodo-, 2',3'-Dibenzoate is a chemically modified nucleoside derivative, specifically engineered for advanced research and synthesis applications. This compound serves as a critical building block and probe in the development of novel pharmaceuticals and biochemical tools, enabling click chemistry and targeted molecular modifications. It is primarily utilized by researchers and process development scientists in the pharmaceutical, biotechnology, and life sciences sectors for drug discovery and nucleic acid chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Bioconjugation & Click Chemistry: The azido group enables efficient, site-specific conjugation with alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling biomolecules.
• Probe Development: Used to create molecular probes for studying enzyme mechanisms, nucleic acid interactions, and cellular uptake pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Oligonucleotide Synthesis: Acts as a modified monomer for incorporating specific functionalities into synthetic oligonucleotides.
• Chemical Biology Tool: Facilitates the exploration of metabolic pathways and the development of activity-based protein profiling (ABPP) reagents.

Basic Information

Product Name	Uridine, 4'-C-Azido-5'-Deoxy-5'-Iodo-, 2',3'-Dibenzoate
CAS No.	139419-02-6
Molecular Formula	C23H18IN3O7
Molecular Weight	575.21 g/mol
Synonyms	4'-Azido-5'-deoxy-5'-iodo-2',3'-di-O-benzoyluridine; 5'-Deoxy-5'-iodo-4'-azido-2',3'-di-O-benzoyluridine; 2',3'-Di-O-benzoyl-5'-deoxy-5'-iodo-4'-azidouridine; 4'-Azido-2',3'-dibenzoate-5'-deoxy-5'-iodouridine; 5'-Iodo-5'-deoxy-4'-azido-2',3'-di-O-benzoyluridine; Uridine, 4'-azido-5'-deoxy-5'-iodo-, 2',3'-dibenzoate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.