Description

2-Bromo-6-Mercaptopurine is a halogenated purine derivative that serves as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its role in modifying the purine scaffold, enabling the development of novel compounds with targeted biological activities. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of nucleoside analogs, potential chemotherapeutic agents, and other bioactive molecules for life science applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and development of novel nucleoside-based drugs and chemotherapeutic agents.
• Biochemical Research: Used in studies investigating purine metabolism, enzyme inhibition, and the structure-activity relationships (SAR) of modified nucleobases.
• Antiviral & Anticancer Agent Synthesis: Serves as a precursor in the synthesis of purine analogs being evaluated for antiviral and anticancer properties.
• Organic Synthesis: Employed as a specialized reagent for introducing bromo and thiol functionalities into complex molecular architectures.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Bromo-6-Mercaptopurine
CAS No.	139244-00-1
Molecular Formula	C5H3BrN4S
Molecular Weight	230.07 g/mol
Synonyms	6-Mercaptopurine, 2-bromo-; 2-Bromo-6-mercaptopurine; 2-Bromo-6-thiopurine; 2-Bromo-6-thioxopurine; 2-Bromo-6-purinethiol; 2-Bromo-Hypoxanthine thiol derivative; Purine-6-thiol, 2-bromo-; 139244-00-1
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Mercaptopurine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.