Description

4-(1-Pyreno)Butylphosphorylinositol is a specialized, high-purity biochemical reagent featuring a pyrene fluorophore conjugated to an inositol phosphate derivative. This compound matters as a critical tool for advanced research in cellular signaling and lipid biochemistry, offering unique fluorescent properties for sensitive detection and tracing applications. It is primarily needed by research scientists and product developers in the pharmaceutical, biotechnology, and life science sectors for probing phosphoinositide pathways and developing diagnostic assays.

Application

• Biochemical Research: As a fluorescent probe for studying phosphatidylinositol (PI) and phosphoinositide (PIP) metabolism, localization, and trafficking in live cells.
• Enzyme Assay Development: Serving as a substrate or inhibitor in high-throughput screening (HTS) assays for kinases, phosphatases, and phospholipases that target inositol phosphates.
• Lipidomics & Analytical Standards: Use as an internal standard or reference compound in mass spectrometry-based lipidomic analysis for accurate quantification of related lipid species.
• Drug Discovery: A tool compound for target validation and mechanistic studies in diseases where phosphoinositide signaling is dysregulated, such as cancer and metabolic disorders.
• Diagnostic Reagent Synthesis: A key intermediate in the synthesis of novel fluorescent conjugates for diagnostic kits and imaging agents.
• Membrane Biophysics: Investigating lipid-protein interactions and membrane dynamics due to its amphiphilic structure and fluorescent reporter.

Basic Information

Product Name	4-(1-Pyreno)Butylphosphorylinositol
CAS No.	139143-25-2
Molecular Formula	C34H35O9P
Molecular Weight	618.62 g/mol
Synonyms	1D-myo-Inositol 1-(4-(1-Pyrenyl)butyl) Hydrogen Phosphate; 4-(1-Pyrenyl)butyl Phosphoinositol; PBPI; Pyrene-butyl-phosphatidylinositol; 4-(1-Pyrenyl)butyl D-myo-inositol 1-phosphate; Fluorescent Inositol Phosphate Derivative; Pyrene-conjugated PI; 1-O-[4-(1-Pyrenyl)butyl]-sn-glycero-3-phospho-1D-myo-inositol (common structural alias)
EINECS	Contact for details

Quality Control

Our 4-(1-Pyreno)Butylphosphorylinositol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data and spectral information are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep the primary container sealed in a secondary container with an appropriate desiccant in a freezer. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown solid or film
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with molecular ion [M-H]-
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.