Description

6-(S-Glutathionyl)-2-tert-Butylhydroquinone is a specialized glutathione conjugate of the antioxidant 2-tert-butylhydroquinone (TBHQ). This compound is significant for its potential role in advanced biochemical research, particularly in studying antioxidant metabolism, cellular protection mechanisms, and redox signaling pathways. It is primarily needed by researchers and developers in the pharmaceutical, nutraceutical, and life science industries for investigating novel therapeutic agents and understanding oxidative stress.

Application

• Biochemical Research: Used as a key reference standard or intermediate in studies of glutathione metabolism and antioxidant pathways.
• Pharmaceutical Development: Investigated for its potential as a prodrug or active pharmaceutical ingredient (API) in formulations targeting oxidative damage.
• Nutraceutical Studies: Serves as a model compound for researching advanced antioxidant systems in dietary supplements.
• Cosmeceutical Research: Explored for potential applications in anti-aging and skin-protectant formulations due to its antioxidant properties.
• Toxicology & Metabolism Studies: Employed to understand the metabolic fate and detoxification pathways of phenolic antioxidants.
• Analytical Standard: Used for method development and calibration in HPLC, LC-MS, or other analytical techniques for quantifying glutathione conjugates.

Basic Information

Product Name	6-(S-Glutathionyl)-2-tert-Butylhydroquinone
CAS No.	139035-71-5
Molecular Formula	C20H31N3O8S
Molecular Weight	473.54 g/mol
Synonyms	6-(S-Glutathionyl)-TBHQ; 2-tert-Butyl-6-(glutathion-S-yl)hydroquinone; Glutathionyl TBHQ; TBHQ Glutathione Conjugate; 6-Glutathionyl-2-tert-butylhydroquinone; 2-tert-Butyl-6-glutathionylhydroquinone; 2-(tert-Butyl)-6-[(2S)-2-[[(2R)-1-[(carboxymethyl)amino]-5-[[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]sulfanylbenzene-1,4-diol (IUPAC); GS-TBHQ
EINECS	Contact for details

Quality Control

Our 6-(S-Glutathionyl)-2-tert-Butylhydroquinone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request. We support research and development with material meeting high-purity standards suitable for pharmaceutical and biochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and easily oxidized; containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.