Description

5Beta-Androstane-3Alpha,17Alpha-Diol-11-One-17Beta-Carboxylic Acid 3-(β-D-Glucuronide) Disodium Salt is a high-purity, conjugated steroid metabolite reference standard, critical for analytical research and diagnostic applications. Its primary value lies in providing a definitive benchmark for the accurate identification and quantification of specific steroid hormone pathways in complex biological matrices. This compound is essential for pharmaceutical R&D laboratories, clinical research institutions, and manufacturers of in-vitro diagnostic (IVD) kits who require reliable, well-characterized materials for method development, validation, and quality control.

Application

• Reference Standard for Analytical Chemistry: Used as a certified reference material (CRM) in HPLC, LC-MS/MS, and GC-MS methods for the precise analysis of steroid metabolites.
• Clinical Research & Diagnostics: Serves as a critical calibrator and control in the development and manufacturing of diagnostic assays for endocrine disorders, congenital adrenal hyperplasia (CAH), and other metabolic conditions.
• Pharmaceutical Development: Employed in pharmacokinetic (PK) and metabolomic studies to understand the biotransformation pathways of steroid-based pharmaceuticals.
• Forensic & Anti-Doping Analysis: Acts as a key standard in confirmatory testing for endogenous steroid profiles in sports drug testing and forensic toxicology.
• Biochemical Research: Utilized in enzymatic studies to investigate steroid glucuronidation pathways and related metabolic processes.

Basic Information

Product Name	5Beta-Androstane-3Alpha,17Alpha-Diol-11-One-17Beta-Carboxylic Acid 3-(β-D-Glucuronide) Disodium Salt
CAS No.	138898-76-7
Molecular Formula	C26H36Na2O11
Molecular Weight	570.55 g/mol
Synonyms	11-Oxoetiocholanolone glucuronide disodium salt; 11-Ketoetiocholanolone glucuronide disodium salt; 5β-Androstane-3α,17α-diol-11-one-17β-carboxylic acid 3-(β-D-glucuronide) disodium salt; 11-Oxo-3α,17α-dihydroxy-5β-androstan-17β-carboxylic acid 3-glucuronide disodium salt; Etiocholanolone-11-one glucuronide disodium; 11-Ketoetiocholanolone 3-glucuronide disodium salt; Steroid metabolite CRM; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Every batch of our 5Beta-Androstane-3Alpha,17Alpha-Diol-11-One-17Beta-Carboxylic Acid 3-(β-D-Glucuronide) Disodium Salt is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for reference standard applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and MS characterization, is supplied with each shipment to guarantee traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.