Description

1,2-Dimyristoyl-Sn-Glycero-3-Diphosphocytidine Potassium Salt is a high-purity, synthetic phospholipid-conjugated nucleotide derivative. This compound is a critical building block in advanced drug delivery research, particularly for the development of lipid nanoparticles (LNPs) used in mRNA vaccines and therapeutics. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, reliable materials for formulation development and process optimization.

Application

• mRNA Vaccine & Therapeutic Formulation: A key ionizable/cationic lipid component in the design and synthesis of novel lipid nanoparticles (LNPs) for encapsulating and delivering nucleic acids.
• Lipid-Based Drug Delivery Systems: Used in the development of liposomes, micelles, and other nanocarriers for targeted delivery of small molecule drugs, proteins, and genetic material.
• Biochemical & Pharmaceutical Research: Serves as a vital reagent in academic and industrial R&D for studying membrane biophysics, cell signaling pathways, and intracellular delivery mechanisms.
• Gene Therapy Development: Employed in non-viral vector systems for the safe and efficient transfection of cells with therapeutic genes.
• Diagnostic Agent Formulation: Can be utilized in the preparation of contrast agents or diagnostic probes for imaging applications.
• Cosmetic & Dermal Delivery: Potential use in advanced cosmetic formulations for the enhanced skin penetration of active ingredients.

Basic Information

Product Name	1,2-Dimyristoyl-Sn-Glycero-3-Diphosphocytidine Potassium Salt
CAS No.	138879-82-0
Molecular Formula	C41H75KN3O16P2
Molecular Weight	975.07 g/mol
Synonyms	CDP-Dimyristoylglycerol Potassium Salt; Cytidine Diphosphate Diacylglycerol (C14:0) Potassium Salt; 1,2-Ditetradecanoyl-sn-glycero-3-cytidine-5'-diphosphate Potassium Salt; DMPC-CDP Potassium Salt; CDP-DMG K+ Salt; Lipid 5 (research context); Ionizable Lipid Intermediate; C14 Lipid-Nucleotide Conjugate
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Diphosphocytidine Potassium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic (moisture-sensitive) nature, the container must be sealed under dry conditions and allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Potassium Content	Theoretical ± 5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.