Description

(1S,2R)-3,3-Dimethoxy-1,2-Cyclobutanedicarboxylic Acid Di-L-Menthyl Ester is a high-purity, chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, stereochemically defined molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly those requiring specific stereochemistry for biological activity.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for transition metal catalysts employed in enantioselective synthesis.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific pesticides and herbicides.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, and specialty materials where precise molecular architecture is required.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry, particularly in studies of cyclobutane chemistry and stereocontrol.

Basic Information

Product Name	(1S,2R)-3,3-Dimethoxy-1,2-Cyclobutanedicarboxylic Acid Di-L-Menthyl Ester
CAS No.	138736-91-1
Molecular Formula	C26H42O8
Molecular Weight	482.61 g/mol
Synonyms	(1S,2R)-3,3-Dimethoxy-1,2-cyclobutanedicarboxylic acid bis[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl] ester; Di-L-Menthyl (1S,2R)-3,3-Dimethoxycyclobutane-1,2-dicarboxylate; (-)-Menthyl (1S,2R)-3,3-Dimethoxycyclobutane-1,2-dicarboxylate; L-Menthyl Ester of 3,3-Dimethoxycyclobutane-1,2-dicarboxylic Acid; Chiral Cyclobutane Diester; (1S,2R)-DMCB Di-L-Menthyl Ester
EINECS	Contact for details

Quality Control

Our (1S,2R)-3,3-Dimethoxy-1,2-Cyclobutanedicarboxylic Acid Di-L-Menthyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.