Description

3-(2-Pyridyldithio)Propionylarginylmonoiodotyrosine is a specialized, high-purity synthetic peptide derivative designed for advanced biochemical research and development. This compound is a critical intermediate in the synthesis of complex bioconjugates, particularly for creating targeted drug delivery systems and diagnostic agents. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on oncology, immunology, and molecular imaging. Its unique structure enables precise cross-linking and labeling applications essential for modern therapeutic and diagnostic platforms.

Application

• Bioconjugation Reagent: A key intermediate for synthesizing antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Research Chemical: Used in biochemical and pharmacological research to study protein-protein interactions and cell signaling pathways.
• Diagnostic Agent Synthesis: Serves as a building block for developing radiopharmaceuticals and fluorescent probes for medical imaging.
• Peptide-Based Drug Development: Employed in the design and synthesis of novel peptide therapeutics with enhanced stability and targeting capabilities.
• Cross-linking Studies: Utilized in proteomics and structural biology to investigate protein structure and function via disulfide bridge formation.
• Pharmaceutical Intermediates: Acts as a critical precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-(2-Pyridyldithio)Propionylarginylmonoiodotyrosine
CAS No.	138191-81-8
Molecular Formula	C24H33IN8O6S2
Molecular Weight	720.61 g/mol
Synonyms	3-(2-Pyridyldithio)propionyl-Arg-monoiodo-Tyr; PDP-Arg-mIodoTyr; S-(2-Pyridylthio)cysteinylarginylmonoiodotyrosine; 3-[2-(Pyridinyldithio)]propionyl-L-arginyl-L-3-iodotyrosine; SPDP derivative of Arg-mIodoTyr; Bioconjugation Peptide 138191-81-8; L-Arginyl-L-3-iodotyrosine, N2-[3-[(2-pyridinyldithio)-1-oxopropyl]]-; Iodotyrosine-containing crosslinking peptide
EINECS	Contact for details

Quality Control

Our 3-(2-Pyridyldithio)Propionylarginylmonoiodotyrosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All materials are subjected to rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.