Description

C16 Globotriaosylceramide (D18:1/16:0) is a specific, high-purity glycosphingolipid with the CAS number 137896-85-6. This well-defined molecular species is critical for research and development in lipidomics and glycolipid biology, offering a consistent standard for analytical and functional studies. It is primarily utilized by researchers in the life sciences, pharmaceutical discovery, and diagnostic development sectors who require precise lipid standards to investigate metabolic pathways, biomarker discovery, and the role of glycosphingolipids in disease.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in mass spectrometry (MS) and liquid chromatography (LC) for the quantification and identification of glycosphingolipids in complex biological samples.
• Cell Biology Studies: Employed in research to study lipid raft composition, cell membrane dynamics, and glycosphingolipid-mediated cell signaling pathways.
• Drug Discovery & Target Validation: Serves as a key substrate or ligand in assays targeting enzymes like glucosylceramide synthase or in studies related to Fabry disease and other lysosomal storage disorders.
• Diagnostic Development: Acts as an essential antigen or standard in the development of immunoassays and diagnostic kits for diseases associated with abnormal glycosphingolipid metabolism.
• Lipidomics Library Construction: A vital component for building comprehensive lipid libraries used in high-throughput screening and metabolic profiling.

Basic Information

Product Name	C16 Globotriaosylceramide (D18:1/16:0)
CAS No.	137896-85-6
Molecular Formula	C64H119NO18
Molecular Weight	1166.64 g/mol
Synonyms	Gb3 (C16:0); Globotriaosylceramide (d18:1/16:0); CD77; Galα1-4Galβ1-4Glcβ1-Cer (d18:1/16:0); Ceramide trihexoside (CTH, C16:0); Pk antigen; GL-3; Gb3Cer (C16:0); 1-O-[α-D-Galactopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-N-hexadecanoylsphing-4-enine
EINECS	Contact for details

Quality Control

Every batch of C16 Globotriaosylceramide is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency suitable for sensitive research applications. Our quality assurance includes comprehensive analytical characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as purity, identity confirmation, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Solvent Content (Residual Solvents)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.