Description

Michellamine A CAS NO 137793-81-8 is a dimeric naphthylisoquinoline alkaloid, a complex natural product originally isolated from the tropical liana *Ancistrocladus korupensis*. This compound is of significant interest to the research and pharmaceutical development communities due to its potent and broad-spectrum antiviral activity, particularly against HIV. It serves as a critical reference standard and a promising lead compound for researchers in medicinal chemistry, virology, and drug discovery.

Application

• Antiviral Research: Primary application as a reference standard and active pharmaceutical ingredient (API) in studies targeting HIV-1 and HIV-2 replication.
• Medicinal Chemistry & Drug Discovery: Used as a lead compound for the synthesis and evaluation of novel analogs with optimized pharmacokinetic and pharmacodynamic properties.
• Biochemical Assay Development: Employed as a key reagent in high-throughput screening (HTS) assays to identify new antiviral agents or mechanisms of action.
• Pharmacological Studies: Utilized in in vitro and in vivo models to investigate efficacy, toxicity, and mechanism of action against retroviruses.
• Academic & Institutional Research: Serves as an essential tool for universities and research institutes focusing on natural product chemistry and virology.
• Pharmaceutical Reference Standard: Critical for quality control, method validation, and regulatory filings in the development of antiviral therapeutics.

Basic Information

Product Name	Michellamine A
CAS No.	137793-81-8
Molecular Formula	C74H78N4O12
Molecular Weight	1191.44 g/mol
Synonyms	Michellamine A; Korupensamine A; ANC 1; Dimeric Naphthylisoquinoline Alkaloid; Anti-HIV Natural Product; 5,5'-Bis(8-hydroxy-6-methoxy-1-methyl-2-isoquinolinyl)-[1,1'-binaphthalene]-4,4',6,6'-tetrol
EINECS	Contact for details

Quality Control

Our Michellamine A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for high-purity research chemicals, ensuring the material's integrity for pharmaceutical and biological research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.