Description

4-Methylumbelliferyl 2-Amino-2-Deoxy-A-D-Glucopyranoside is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific enzymatic activity. This compound is critical for researchers and quality control laboratories requiring precise biochemical assays. It is primarily utilized in the life sciences, pharmaceutical development, and diagnostic industries for studying glycosidase enzymes, such as N-acetyl-β-D-glucosaminidase.

Application

• Enzymatic Assay Substrate: A key fluorogenic substrate for the detection and kinetic study of β-N-acetylglucosaminidase and related glycosidases.
• Diagnostic Reagent Manufacturing: Used in the production of diagnostic kits for lysosomal storage disorders and other metabolic diseases.
• Biochemical Research: Essential tool in academic and industrial research for investigating carbohydrate metabolism and enzyme mechanisms.
• Pharmaceutical Quality Control: Employed in purity and activity testing of enzyme-based therapeutics and biologics.
• Microbiology Studies: Applied in assays to characterize bacterial or fungal enzymes for identification and research purposes.
• High-Throughput Screening (HTS): Suitable for use in automated screening platforms to identify enzyme inhibitors or activators for drug discovery.

Basic Information

Product Name	4-Methylumbelliferyl 2-Amino-2-Deoxy-A-D-Glucopyranoside
CAS No.	137687-00-4
Molecular Formula	C₁₆H₁₉NO₈
Molecular Weight	353.33 g/mol
Synonyms	4-MU-2-Amino-2-deoxy-α-D-glucopyranoside; 4-Methylumbelliferyl N-acetyl-α-D-glucosaminide (common application name); 4-MU-α-GlcNAc; 4-Methylumbelliferyl α-N-acetylglucosaminide; 4-MU-α-NAG; Fluorogenic NAG substrate; 7-Hydroxy-4-methylcoumarin 2-acetamido-2-deoxy-α-D-glucopyranoside
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl 2-Amino-2-Deoxy-A-D-Glucopyranoside is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Fluorogenic Activity	Functional in standard enzyme assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.