Description

Chlorpromazine-D3 is a deuterium-labeled analog of the classic antipsychotic agent chlorpromazine, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in complex biological matrices. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics industries who require precise measurement of chlorpromazine and its metabolites.

Application

• Primary use as an internal standard for the quantification of chlorpromazine in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and Gas Chromatography-Mass Spectrometry (GC-MS) methods.
• Metabolite profiling and pharmacokinetic studies in pharmaceutical research and development.
• Forensic analysis and toxicology screening for the accurate determination of chlorpromazine levels.
• Quality control and assurance in the manufacturing of chlorpromazine-based pharmaceutical formulations.
• Use in clinical research to study drug metabolism and therapeutic drug monitoring (TDM).
• Stable isotope dilution analysis in academic and industrial research settings.

Basic Information

Product Name	Chlorpromazine-D3
CAS No.	136765-28-1
Molecular Formula	C17H16D3ClN2S
Molecular Weight	321.88 g/mol (deuterated form)
Synonyms	2-Chloro-10-[3-(trideuteriomethylamino)propyl]phenothiazine; Chlorpromazine-d3; Largactil-d3; Thorazine-d3; 3-(2-Chloro-10H-phenothiazin-10-yl)-N-(trideuteriomethyl)propan-1-amine; Deuterated Chlorpromazine; Chlorpromazine Internal Standard
EINECS	Contact for details

Quality Control

Every batch of Chlorpromazine-D3 is manufactured and analyzed under strict quality management protocols to ensure the highest standards of isotopic purity and chemical identity. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry, cool, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.