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Dimyristoylphosphatidylinositol CAS NO 136655-51-1


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CAS No.:136655-51-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dimyristoylphosphatidylinositol is a synthetic, high-purity phospholipid derivative of phosphatidylinositol, featuring two myristoyl (C14:0) fatty acid chains. This compound is a critical building block for creating advanced lipid-based delivery systems and biomimetic membranes due to its defined structure and physicochemical properties. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing liposomal drug formulations, diagnostic agents, and model membrane systems for biophysical studies.

Application

  • Liposomal Drug Delivery: A key phospholipid component for formulating stable, targeted liposomes for cancer therapeutics, vaccines, and nucleic acid delivery.
  • Biomimetic Membrane Research: Used to create defined model membranes (e.g., vesicles, supported lipid bilayers) for studying protein-lipid interactions, membrane trafficking, and signaling pathways.
  • Pharmaceutical Excipient: Serves as a functional excipient in advanced parenteral formulations to enhance drug solubility, stability, and bioavailability.
  • Diagnostic Reagent Manufacturing: Employed in the production of contrast agents and other in vitro diagnostic tools requiring specific lipid compositions.
  • Cell Biology & Biochemistry: A vital reagent for studying the role of phosphoinositides in cellular processes such as signal transduction and cytoskeletal organization.
  • Cosmetic Actives Carrier: Utilized in high-end cosmetic formulations as a biocompatible carrier for active ingredients, improving skin penetration and efficacy.

Basic Information

Product Name Dimyristoylphosphatidylinositol
CAS No. 136655-51-1
Molecular Formula C41H77O13P
Molecular Weight 809.01 g/mol
Synonyms 1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-myo-inositol); DMPI; 1,2-Ditetradecanoyl-sn-glycero-3-phospho-(1'-myo-inositol); Phosphatidylinositol(14:0/14:0); PI(14:0/14:0); 1,2-Dimyristoylphosphatidylinositol; (3S)-2,3-Bis(tetradecanoyloxy)propyl (1R,2R,3S,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl phosphate
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Quality Control

Our Dimyristoylphosphatidylinositol is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and GMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and critical impurity profiles. We adhere to relevant industry standards, and custom purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC/MS) Conforms
Assay (HPLC) ≥ 95%
Purity (TLC) Single spot
Solubility Soluble in chloroform, methanol, DMSO
Water Content (KF) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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