Description

Adenosine 3'-Phosphate 5'-Methylenephosphosulfate is a specialized nucleotide derivative, also known as a sulfated adenosine phosphonate, that serves as a critical biochemical tool and potential synthetic intermediate. Its unique structure, featuring a methylenephosphosulfate linkage, makes it valuable for studying enzyme mechanisms, particularly those involving sulfuryl transfer and nucleotide metabolism. This high-purity compound is essential for researchers and manufacturers in pharmaceutical development, biochemical research, and enzymology, where precise molecular probes are required.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for sulfuryltransferases, kinases, and phosphatases.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the synthesis and development of novel nucleotide-based therapeutics.
• Enzymology: Acts as a mechanistic probe to investigate the catalytic pathways of enzymes involved in phosphate and sulfate transfer reactions.
• Diagnostic Reagent Manufacturing: Potential use in formulating specialized assay kits for clinical diagnostics and life science research.
• Metabolic Pathway Analysis: Employed in tracer studies to elucidate complex biochemical pathways in cellular systems.
• Academic Research: A vital tool for universities and research institutes conducting fundamental studies in bioorganic chemistry and molecular biology.

Basic Information

Product Name	Adenosine 3'-Phosphate 5'-Methylenephosphosulfate
CAS No.	136439-85-5
Molecular Formula	C11H16N5O12P2S
Molecular Weight	528.28 g/mol
Synonyms	Adenosine 3'-phosphate 5'-(methylenephosphosulfate); 3'-AMP-5'-(methylenephosphosulfate); Adenosine 3'-monophosphate 5'-(methylenephosphosulfate); 5'-O-[(Phosphonosulfonyl)methyl]-adenosine 3'-phosphate; APS-CH2-P; Methylenephosphosulfate adenosine derivative; Sulfated adenosine phosphonate analog
EINECS	Contact for details

Quality Control

Every batch of Adenosine 3'-Phosphate 5'-Methylenephosphosulfate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to stringent in-house quality standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.