Description

1-o-Hexadecyl-2-Acrylyl-Sn-Glycero-3-Phosphocholine is a synthetic, chemically defined phospholipid analog, specifically a lysophosphatidylcholine derivative with a polymerizable acrylyl group. This compound is a critical building block in advanced materials science and biomedical research, enabling the creation of functionalized lipid membranes and targeted delivery systems. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and nanotechnology sectors for applications requiring precise molecular engineering of lipid-based structures.

Application

• Liposome & Nanoparticle Functionalization: As a key precursor for creating polymerizable liposomes and nanoparticles with enhanced stability and controlled release properties.
• Biomimetic Membrane Research: For constructing stable, synthetic cell membranes and lipid bilayers to study membrane protein interactions and cellular processes.
• Targeted Drug Delivery Systems: Enables the synthesis of ligand-conjugated or stimuli-responsive lipid carriers for site-specific therapeutic delivery.
• Polymerizable Lipid Synthesis: Serves as a monomeric unit in the development of cross-linked lipid networks and hydrogels for tissue engineering scaffolds.
• Diagnostic Agent Development: Used in formulating contrast agents or probes for imaging techniques like MRI and fluorescence microscopy.
• Surface Modification & Coatings: Applied to modify material surfaces with bioactive lipid layers to improve biocompatibility and specific cellular interactions.

Basic Information

Product Name	1-o-Hexadecyl-2-Acrylyl-Sn-Glycero-3-Phosphocholine
CAS No.	135566-25-5
Molecular Formula	C₂₇H₅₂NO₇P
Molecular Weight	533.68 g/mol
Synonyms	1-Hexadecyl-2-acryloyl-sn-glycero-3-phosphocholine; 2-Acryloyl-1-hexadecyl-sn-glycero-3-phosphocholine; Acryloyl Lyso PC (C16:0); Polymerizable Lyso Phosphatidylcholine; Lyso PC-C16-Acryl; 1-Palmitoyl-2-acryloyl-sn-glycero-3-phosphocholine (common naming variant); A-LysoPC(16:0/0:0); Acrylated Lysolectihin C16
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Acrylyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, batch-to-batch consistency, and compliance with your experimental protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. Store away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.