Description

Crambescidin 816 is a potent guanidine alkaloid of marine origin, specifically isolated from the sponge *Crambe crambe*. This compound is of significant interest due to its unique biological profile, serving as a valuable reference standard and a key scaffold in pharmacological research. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for drug discovery programs. The product is supplied with a CAS No. of 135257-45-3.

Application

• Biomedical Research Standard: Used as a high-purity reference material for analytical method development and validation in laboratories.
• Pharmacological Studies: Acts as a critical tool compound for investigating calcium channel blocking activity and other ion channel interactions.
• Antiviral & Antitumor Screening: Employed in bioassays to evaluate potential efficacy against various viral strains and cancer cell lines.
• Natural Product Chemistry: Serves as a benchmark for the isolation, identification, and structural elucidation of related marine-derived alkaloids.
• Lead Compound Optimization: Provides a chemical foundation for medicinal chemistry programs aimed at developing novel therapeutic agents.
• Academic Research: Utilized in university and institutional settings for fundamental studies in marine biochemistry and chemical ecology.

Basic Information

Product Name	Crambescidin 816
CAS No.	135257-45-3
Molecular Formula	C₄₃H₇₁N₁₃O₈
Molecular Weight	922.12 g/mol
Synonyms	Crambescidin 816; Crambescidin-816; Crambescidin 800; Crambescidin-800; 13b,14,15,16,17,18,19,20,21,22,23,23a-Dodecahydro-17-hydroxy-12,20,23-trimethyl-10H,12H,23H-imidazo[4,5-k]pyrrolo[1,2-a][1,8]diazacyclopentadecine-10,13(11H)-dione; (13bS,17S,20R,23aS)-13b,14,15,16,17,18,19,20,21,22,23,23a-Dodecahydro-17-hydroxy-12,20,23-trimethyl-10H,12H,23H-imidazo[4,5-k]pyrrolo[1,2-a][1,8]diazacyclopentadecine-10,13(11H)-dione
EINECS	Contact for details

Quality Control

Our Crambescidin 816 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.