Description

3-Ribofuranosylisoguanosine 5'-Diphosphate is a specialized nucleotide analog of significant interest in biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying enzyme kinetics, nucleic acid metabolism, and cellular signaling pathways. It is primarily utilized by research institutions, diagnostic manufacturers, and biotechnology companies engaged in advanced life science applications.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays, particularly for kinases, phosphatases, and other nucleotide-processing enzymes.
• Nucleic Acid Chemistry: Acts as a precursor or modified nucleotide for the synthesis of oligonucleotides with specific biological activities.
• Drug Discovery: Serves as a key intermediate in the development of nucleotide-based therapeutics targeting viral infections, cancer, and metabolic disorders.
• Diagnostic Development: Employed in the formulation of assay kits for monitoring specific enzymatic activities or metabolic pathways in clinical and research settings.
• Cell Signaling Studies: Utilized to investigate purinergic signaling pathways and the role of nucleotide derivatives in cellular communication.

Basic Information

Product Name	3-Ribofuranosylisoguanosine 5'-Diphosphate
CAS No.	135052-71-0
Molecular Formula	C15H22N5O15P2
Molecular Weight	574.31 g/mol
Synonyms	3-β-D-Ribofuranosylisoguanosine 5'-diphosphate; Iso-GDP; Isoguanosine diphosphate; 3-Ribosylisoguanosine 5'-diphosphate; 3-β-D-Ribofuranosyl-2-oxo-6-amino-1H-purin-9-yl 5'-diphosphate; 3-β-D-Ribofuranosyl-6-amino-2-oxopurine 5'-diphosphate
EINECS	Contact for details

Quality Control

Our 3-Ribofuranosylisoguanosine 5'-Diphosphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.