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Phenylalanyl-Threonyl-Arginyl-Phenylalaninamide CAS NO 135014-49-2
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CAS No.:135014-49-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Phenylalanyl-Threonyl-Arginyl-Phenylalaninamide is a synthetic tetrapeptide with the sequence Phe-Thr-Arg-Phe-NH₂. This compound is of significant interest in biochemical and pharmaceutical research due to its specific peptide sequence, which can be designed to mimic or interfere with biological processes. It serves as a critical intermediate or reference standard for researchers and manufacturers in the life sciences sector. Key target industries include pharmaceutical R&D, biotechnology, and academic institutions focused on peptide chemistry and drug discovery.
Application
- Pharmaceutical Research: Used as a reference standard or intermediate in the development of novel therapeutic peptides and peptidomimetics.
- Biochemical Studies: Serves as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
- Drug Discovery: Acts as a building block or a lead compound in high-throughput screening libraries for identifying new bioactive molecules.
- Academic Research: Employed in universities and research institutes for studying peptide synthesis, structure-activity relationships (SAR), and molecular recognition.
- Bioconjugation: Potential use in the synthesis of peptide-protein conjugates or labeled probes for diagnostic applications.
Basic Information
| Product Name | Phenylalanyl-Threonyl-Arginyl-Phenylalaninamide |
| CAS No. | 135014-49-2 |
| Molecular Formula | C₃₂H₄₇N₉O₆ |
| Molecular Weight | 653.78 g/mol |
| Synonyms | Phe-Thr-Arg-Phe-NH₂; FTKF-NH₂; H-Phe-Thr-Arg-Phe-NH₂; L-Phenylalanyl-L-threonyl-L-arginyl-L-phenylalaninamide; FTRF-amide; Tetrapeptide Sequence 46-49 (Human Parathyroid Hormone-related Protein); PTHrP(46-49) amide; Phenylalanine-threonine-arginine-phenylalanine amide |
| EINECS | Contact for details |
Quality Control
Our Phenylalanyl-Threonyl-Arginyl-Phenylalaninamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with research-grade specifications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms |
| Purity (HPLC) | ≥ 95.0% |
| Assay (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 5.0% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Optical Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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