Description

Uridine 5'-Phosphoric (1-Hexadecanesulfonic)Anhydride is a specialized nucleotide derivative and activated intermediate used in synthetic organic chemistry and biochemistry. This compound is critical for the controlled synthesis of modified nucleotides and oligonucleotides, enabling precise chemical modifications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, molecular biology applications, and the development of nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs and prodrugs with potential antiviral or anticancer activity.
• Oligonucleotide Synthesis: Acts as an activated monomer for the controlled, stepwise chemical synthesis of modified DNA or RNA strands in solid-phase or solution-phase protocols.
• Bioconjugation & Labeling: Used to attach reporter molecules (e.g., fluorophores, biotin) or functional groups to nucleosides for diagnostic assays and imaging probes.
• Enzymology Studies: Serves as a substrate analog or inhibitor in studies of kinase, phosphorylase, and other nucleotide-processing enzymes.
• Prodrug Development: Facilitates the creation of lipophilic prodrugs of nucleoside monophosphates to enhance cellular uptake and bioavailability.
• Chemical Biology Research: A versatile tool for exploring nucleic acid structure, function, and metabolism in academic and industrial R&D settings.

Basic Information

Product Name	Uridine 5'-Phosphoric (1-Hexadecanesulfonic)Anhydride
CAS No.	134282-88-5
Molecular Formula	C25H45N2O12PS
Molecular Weight	628.66 g/mol
Synonyms	Uridine 5'-(Hexadecanesulfonyl Phosphate); 5'-Uridylic Acid, Anhydride with 1-Hexadecanesulfonic Acid; Uridine 5'-Monophosphate Palmitoyl Sulfonate Anhydride; 1-Hexadecanesulfonic Acid, Anhydride with Uridine 5'-Phosphate; Uridine-5'-phosphoric acid 1-hexadecanesulfonic acid anhydride; Activated Uridine Monophosphate; UMP-C16 Ester
EINECS	Contact for details

Quality Control

Our Uridine 5'-Phosphoric (1-Hexadecanesulfonic)Anhydride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, freezer. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in organic solvents (e.g., DMSO, DMF, acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.