Description

Boc-Leu-Arg-Arg-Amc Hcl is a specialized, protected peptide substrate designed for high-precision biochemical research. This compound is critical for studying protease activity, particularly in the context of enzyme kinetics and inhibitor screening. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on enzymology and drug discovery.

Application

• Protease Enzyme Assays: Acts as a fluorogenic substrate for the study of trypsin-like serine proteases, including furin and other proprotein convertases.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors for therapeutic development.
• Biochemical Research: Serves as a key tool for investigating enzymatic mechanisms, cleavage specificity, and kinetic parameters in vitro.
• Diagnostic Development: Employed in the design and calibration of diagnostic assays that measure specific protease activity in biological samples.

Basic Information

Product Name	Boc-Leu-Arg-Arg-Amc Hcl
CAS No.	133605-56-8
Molecular Formula	C30H56N12O7 • xHCl
Molecular Weight	Contact for details
Synonyms	Boc-Leu-Arg-Arg-AMC hydrochloride; t-Butyloxycarbonyl-Leucyl-Arginyl-Arginyl-7-Amino-4-Methylcoumarin hydrochloride; Boc-L-R-R-AMC HCl; Furin Substrate Boc-Leu-Arg-Arg-AMC; Fluorogenic Protease Substrate V; Proprotein Convertase Substrate; PC Substrate; t-Boc-Leu-Arg-Arg-Amc • HCl
EINECS	Contact for details

Quality Control

Our Boc-Leu-Arg-Arg-Amc Hcl is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay conditions. We adhere to GMP principles for laboratory chemicals, ensuring traceability and documentation for our life science customers.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Assay (Enzymatic)	≥ 90% of theoretical activity
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.