Description

5-Carboxytetrahydroalstonine is a specialized indole alkaloid derivative with significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial high-purity building block for developing novel therapeutic agents and complex molecular architectures. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel alkaloid-based drug candidates targeting central nervous system disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Reference Standard: Serves as an analytical standard for quality control and method development in phytochemical and pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the biosynthesis and biological activity of complex indole alkaloids.
• Fine Chemical Synthesis: A valuable chiral building block for the asymmetric synthesis of complex natural products and specialty chemicals.

Basic Information

Product Name	5-Carboxytetrahydroalstonine
CAS No.	133541-29-4
Molecular Formula	C22H26N2O4
Molecular Weight	382.46 g/mol
Synonyms	5-Carboxytetrahydroalstonine; Tetrahydroalstonine-5-carboxylic acid; 19,20-Didehydro-10,17-dimethoxy-2,16-didehydrocuran-17-ol-16-carboxylic acid methyl ester; Alstonine derivative; (19E)-10,17-Dimethoxy-2,16-didehydrocuran-17-ol-16-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Carboxytetrahydroalstonine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.