Description

L-Lysine(Boc) Hydroxysuccinimide Ester is a high-purity, protected amino acid derivative widely used as a key building block in peptide synthesis. This compound matters for its role in facilitating efficient and selective amide bond formation, particularly in solid-phase peptide synthesis (SPPS) and bioconjugation strategies. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries developing peptide-based therapeutics, diagnostic probes, and novel biomaterials.

Application

• Peptide Synthesis: A crucial reagent in solid-phase and solution-phase peptide synthesis for the controlled incorporation of lysine residues.
• Bioconjugation: Used to label proteins, antibodies, and other biomolecules with fluorescent dyes, affinity tags, or drug payloads.
• Pharmaceutical Intermediates: Serves as a key intermediate in the production of complex peptide active pharmaceutical ingredients (APIs).
• Proteomics Research: Employed in the synthesis of peptide standards, enzyme substrates, and inhibitors for biochemical assays.
• Material Science: Facilitates the creation of peptide-polymer conjugates and functionalized surfaces for biomedical applications.
• Antibody-Drug Conjugate (ADC) Development: Used in the linker chemistry for attaching cytotoxic agents to monoclonal antibodies.

Basic Information

Product Name	L-Lysine(Boc) Hydroxysuccinimide Ester
CAS No.	133506-39-5
Molecular Formula	C16H27N3O6
Molecular Weight	357.41 g/mol
Synonyms	Nε-Boc-L-lysine N-hydroxysuccinimide ester; Boc-Lys-OH N-succinimidyl ester; Nα-Boc-Nε-(tert-butoxycarbonyl)-L-lysine N-hydroxysuccinimide ester; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Boc-Lys(Boc)-OSu; Fmoc-Lys(Boc)-OSu; Nα-Boc-Nε-Boc-L-lysine hydroxysuccinimide ester; Nε-Boc-L-lysine, N-succinimidyl ester
EINECS	Contact for details

Quality Control

Our L-Lysine(Boc) Hydroxysuccinimide Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to ensure enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.