Description

18-Hydroxy Arachidonic Acid is a bioactive hydroxy fatty acid and a key oxidized metabolite of arachidonic acid. This compound is significant for its role as a signaling molecule and intermediate in the study of lipid metabolism and inflammatory pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for biochemical research, drug discovery, and as a reference standard.

Application

• Biochemical Research: Used as a critical standard and reagent in lipidomics and eicosanoid research to study metabolic pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the development of anti-inflammatory and metabolic disorder therapeutics.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the role of oxylipins in cellular communication and inflammatory responses.
• Analytical Reference Standard: Essential for the calibration of analytical equipment (HPLC, LC-MS) to ensure accurate quantification in complex biological samples.
• Enzymology: Used as a substrate to study the activity and inhibition of cytochrome P450 and lipoxygenase enzymes.

Basic Information

Product Name	18-Hydroxy Arachidonic Acid
CAS No.	133268-58-3
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	18-HETE; 18-Hydroxyeicosatetraenoic Acid; (5Z,8Z,11Z,14Z)-18-Hydroxyicosa-5,8,11,14-tetraenoic Acid; AA-18-OH; 18-Hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 18-Hydroxyarachidonate; 18-Hydroxy-AA
EINECS	Contact for details

Quality Control

Our 18-Hydroxy Arachidonic Acid is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO, and organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.