Description

(S)-1-Tosyloxy-3-Buten-1-Ol is a high-value chiral building block and key synthetic intermediate. This compound matters for its role in facilitating stereoselective synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug candidates.
• Asymmetric Synthesis: Used in stereocontrolled carbon-carbon bond-forming reactions to introduce the (S)-configured alcohol functionality.
• Natural Product Synthesis: Serves as a starting material or intermediate in the total synthesis of complex natural products with biological activity.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is required for efficacy.
• Ligand and Catalyst Preparation: Useful for the preparation of chiral ligands and organocatalysts used in enantioselective transformations.
• Polymer Science: Can be utilized to introduce chiral centers into specialty polymers and functional materials.

Basic Information

Product Name	(S)-1-Tosyloxy-3-Buten-1-Ol
CAS No.	133095-74-6
Molecular Formula	C11H14O3S
Molecular Weight	226.29 g/mol
Synonyms	(S)-1-[(4-Methylphenyl)sulfonyl]oxy-3-buten-1-ol; (S)-1-(p-Toluenesulfonyloxy)-3-buten-1-ol; (S)-3-Buten-1-ol, 1-(4-methylbenzenesulfonate); (S)-1-Tosyloxy-3-buten-1-ol; (S)-1-Hydroxy-3-butene-1-yl p-toluenesulfonate; (S)-1-O-Tosyl-3-buten-1-ol; (S)-1-(Tosyloxy)but-3-en-1-ol; (S)-But-3-ene-1,1-diol 1-(4-methylbenzenesulfonate)
EINECS	Contact for details

Quality Control

Our (S)-1-Tosyloxy-3-Buten-1-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.