Description

C8-Sphingosine CAS NO 133094-50-5 is a synthetic, short-chain analog of the naturally occurring sphingolipid backbone, sphingosine. This compound is a critical biochemical tool and building block for research into sphingolipid metabolism, cell signaling, and apoptosis. It is primarily utilized by researchers and developers in the life sciences, pharmaceutical, and cosmetic industries. Its defined structure and purity make it essential for studying lipid-mediated pathways and developing novel therapeutic and bioactive agents.

Application

• Biochemical Research: As a key intermediate and standard in the study of sphingolipid metabolism, ceramide synthesis, and cell signaling pathways.
• Pharmaceutical Development: Used as a reference compound and synthetic precursor in the discovery of drugs targeting cancer, inflammatory diseases, and neurological disorders.
• Cosmetic Science: Incorporated into research for developing advanced skincare formulations aimed at modulating skin barrier function and cellular communication.
• Cell Biology Studies: Employed to investigate the role of sphingolipids in apoptosis (programmed cell death), differentiation, and stress responses in vitro.
• Enzyme Assays: Serves as a substrate or inhibitor in enzymatic assays for sphingosine kinases, ceramidases, and other lipid-modifying enzymes.
• Lipidomics: Used as an internal standard for the accurate quantification of sphingolipids and their metabolites via mass spectrometry techniques.

Basic Information

Product Name	C8-Sphingosine
CAS No.	133094-50-5
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	D-erythro-C8-Sphingosine; (2S,3R)-2-Amino-3-hydroxyoctadec-4-yne (Note: This is the IUPAC for C18 base, C8 is a truncated analog); Octanoylsphingosine; N-Octanoylsphingosine; Sphingosine C8; C8 Ceramide precursor; 2-Amino-3-hydroxyoct-4-yn-1-ol (derived); Short-chain sphingosine
EINECS	Contact for details

Quality Control

Every batch of C8-Sphingosine is manufactured and analyzed under strict quality management protocols to ensure high purity and consistency. Our products undergo rigorous quality testing, including chromatographic purity assays and identity confirmation, to meet the exacting standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.