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D-Glycero-D-Galacto-2-Nonulopyranosonic Acid, 5-(Acetylamino)-2-Chloro-2,3,5-Trideoxy-, Methyl Ester, 4,7,8,9-Tetraacetate CAS NO 132883-18-2


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CAS No.:132883-18-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Glycero-D-Galacto-2-Nonulopyranosonic Acid, 5-(Acetylamino)-2-Chloro-2,3,5-Trideoxy-, Methyl Ester, 4,7,8,9-Tetraacetate is a complex, high-purity synthetic intermediate belonging to the class of sialic acid derivatives. This compound is of critical importance for pharmaceutical research and development, particularly in the synthesis of novel glycoconjugates and carbohydrate-based therapeutics. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in advanced medicinal chemistry and glycobiology.

Application

  • Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the development of sialic acid analogs and glycomimetics with potential therapeutic applications.
  • Glycobiology Research: Used in the study of carbohydrate-protein interactions, cell signaling, and the role of sialic acids in biological processes.
  • Antiviral Drug Development: Investigated as a precursor for compounds targeting viral neuraminidases and other carbohydrate-processing enzymes.
  • Diagnostic Reagent Production: Employed in the synthesis of labeled probes and standards for diagnostic assays and analytical methods.
  • Chemical Biology Tool Development: Utilized to create molecular probes for studying glycosylation pathways and metabolic engineering.
  • Fine Chemical Manufacturing: Acts as a specialized intermediate for the custom synthesis of complex, high-value organic molecules.

Basic Information

Product Name D-Glycero-D-Galacto-2-Nonulopyranosonic Acid, 5-(Acetylamino)-2-Chloro-2,3,5-Trideoxy-, Methyl Ester, 4,7,8,9-Tetraacetate
CAS No. 132883-18-2
Molecular Formula C24H34ClNO14
Molecular Weight 596.0 g/mol (approx.)
Synonyms 5-Acetamido-2-chloro-2,3,5-trideoxy-D-glycero-D-galacto-non-2-enopyranosonic Acid Methyl Ester Tetraacetate; Methyl 5-acetamido-2-chloro-2,3,5-trideoxy-D-glycero-D-galacto-non-2-enopyranosonate Tetraacetate; 2-Chloro Sialic Acid Methyl Ester Tetraacetate; Sialyl Chloride Derivative; Neu5Ac2en Derivative; CAS 132883-18-2
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Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications from HPLC, NMR, and mass spectrometry are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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