Description

2'-Deoxypuromycin is a specialized nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial building block and reference standard in the synthesis and study of novel therapeutic agents, particularly in the fields of antiviral and anticancer research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for advanced drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway investigations.
• Antiviral Agent Development: Serves as a core structural component for researching compounds targeting viral polymerases.
• Oncology Research: Investigated for its potential role in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis.
• Academic & Institutional R&D: Employed in university and research institute laboratories for fundamental studies in medicinal chemistry.
• Process Development & Scale-up: Utilized by process chemists for optimizing synthetic routes and manufacturing processes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2'-Deoxypuromycin
CAS No.	132370-70-8
Molecular Formula	C11H15N5O4
Molecular Weight	281.27 g/mol
Synonyms	2'-Deoxy-puromycin; Puromycin, 2'-deoxy-; 9-[(2R,3S,5R)-3-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(dimethylamino)-9H-purin-2-amine; 2'-Deoxyadenosine, N6,N6-dimethyl-; 6-(Dimethylamino)-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-2-amine
EINECS	Contact for details

Quality Control

Our 2'-Deoxypuromycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data. While produced to meet general research-grade standards, specifications can be aligned with specific project requirements for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.