Description

1-o-Hexadecyl-2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is a synthetic, structured phospholipid featuring a saturated hexadecyl (C16:0) chain at the sn-1 position and the highly unsaturated docosahexaenoyl (DHA, C22:6) chain at the sn-2 position. This unique molecular architecture makes it a critical component for advanced lipid-based delivery systems and membrane research, offering superior fluidity and biocompatibility. It is primarily utilized by researchers and formulators in the pharmaceutical, nutraceutical, and advanced biomaterials sectors for developing targeted drug delivery vehicles, specialized liposomes, and model membrane systems.

Application

• Liposome & Nanoparticle Formulation: A key structural lipid for creating stealth liposomes, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs) for targeted drug and gene delivery.
• Biomembrane & Cell Biology Research: Used to construct artificial membranes and lipid bilayers with specific fluidity and fusion properties to study membrane protein interactions and cellular processes.
• Nutraceutical Encapsulation: Employed in the encapsulation of sensitive bioactive compounds, such as ω-3 fatty acids (including DHA itself), vitamins, and antioxidants, to enhance stability and bioavailability.
• Diagnostic Reagents: Serves as a component in diagnostic kits and assays that require specific lipid environments for optimal performance.
• Cosmetic Actives Delivery: Incorporated into high-end cosmetic formulations to improve the skin penetration and stability of active ingredients.

Basic Information

Product Name	1-o-Hexadecyl-2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine
CAS No.	132213-85-5
Molecular Formula	C46H84NO8P
Molecular Weight	810.14 g/mol
Synonyms	16:0-22:6 PC; 1-Hexadecyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine; DHA-PC; C16:0/C22:6 PC; 1-O-Hexadecyl-2-docosahexaenoyl-phosphatidylcholine; Plasmalogen PC (16:0/22:6); PAF C-16 DHA; Glycerophosphocholine derivative (C16 alkyl, C22:6 acyl)
EINECS	Contact for details

Quality Control

Our 1-o-Hexadecyl-2-Docosahexaenoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and isomer confirmation, NMR for structural verification, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (argon or nitrogen). This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC, Area %)	≥ 95.0%
Solvent Content (Residual Solvents)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%
Peroxide Value	≤ 5.0 mEq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.