Description

Ramosetron CAS NO 132036-90-9 is a highly potent and selective serotonin 5-HT₃ receptor antagonist. This compound is of significant importance in the pharmaceutical industry for its antiemetic properties, effectively preventing nausea and vomiting. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of therapeutic agents for managing chemotherapy-induced and postoperative nausea and vomiting.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key active component in prescription antiemetic medications.
• Oncology Supportive Care: Formulation into injectable or oral drugs to prevent nausea and vomiting associated with chemotherapy.
• Postoperative Care: Development of treatments to manage nausea and vomiting following surgical procedures.
• Clinical Research: Used as a reference standard or investigational compound in pharmacological and pharmacokinetic studies.
• Drug Development: Serves as a lead compound for synthesizing novel derivatives with improved efficacy or reduced side effects.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing emesis in animals.

Basic Information

Product Name	Ramosetron
CAS No.	132036-90-9
Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34 g/mol
Synonyms	(R)-5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole; Ramosetron Hydrochloride; Y-25130; Nasea; Irribow; 5-HT3 Receptor Antagonist Y-25130
EINECS	Contact for details

Quality Control

Our Ramosetron is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.