Description

Ramosetron CAS NO 132036-88-5 is a potent and selective serotonin 5-HT₃ receptor antagonist. This compound is of significant importance in the pharmaceutical industry for its antiemetic properties, effectively preventing nausea and vomiting. It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of therapeutic agents targeting chemotherapy-induced and postoperative nausea and vomiting (CINV and PONV).

Application

• Active Pharmaceutical Ingredient (API) in antiemetic medications.
• Research and development of novel 5-HT₃ receptor antagonists.
• Formulation of injectable solutions for acute nausea control.
• Production of oral dosage forms for preventative care.
• Reference standard for analytical and quality control laboratories.
• Pharmacological studies investigating serotonin receptor pathways.

Basic Information

Product Name	Ramosetron
CAS No.	132036-88-5
Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34 g/mol
Synonyms	(R)-ramosetron; Ramosetron hydrochloride; Y-25130; N-[(3R)-1-methyl-3-pyrrolidinyl]-1H-indazole-3-carboxamide; 1H-Indazole-3-carboxamide, N-[(3R)-1-methyl-3-pyrrolidinyl]-; UNII-7U8F1O5Y2P; Y 25130; Ramosetronum
EINECS	Contact for details

Quality Control

Our Ramosetron is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) confirming identity, purity, and compliance with in-house specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.