Description

Pregnenediol Sulfate Sodium is a high-purity, water-soluble sodium salt derivative of pregnanediol, a key progesterone metabolite. This compound serves as a critical reference standard and analytical reagent for precise hormone metabolite quantification in clinical and research settings. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions specializing in endocrinology and steroid biochemistry.

Application

• Clinical Diagnostic Reference Standard: Calibration and validation of assays (e.g., LC-MS/MS, GC-MS, ELISA) for measuring pregnanediol glucuronide and sulfate metabolites in urine and serum.
• Pharmaceutical Research: Used as an analytical standard in the development and quality control of steroid-based pharmaceuticals and in metabolic pathway studies.
• Endocrinology & Fertility Monitoring: Essential for research and tests related to ovarian function, luteal phase assessment, and monitoring progesterone production during pregnancy.
• Biochemical Research: Investigation of steroid sulfation pathways, enzyme activity (sulfotransferases), and hormone conjugation/deconjugation mechanisms.
• Veterinary Diagnostics: Applied in reproductive health monitoring and research for various animal species.

Basic Information

Product Name	Pregnenediol Sulfate Sodium
CAS No.	131320-06-4
Molecular Formula	C21H31NaO5S
Molecular Weight	418.52 g/mol
Synonyms	Pregnanediol Sulfate Sodium Salt; 5β-Pregnane-3α,20α-diol 3-Sulfate Sodium Salt; 3α,20α-Dihydroxy-5β-pregnan-3-yl Sulfate Sodium Salt; Sodium Pregnanediol Sulfate; PDS-Na; Pregnane-3α,20α-diol 3-Sulfate Sodium; 20α-Hydroxypregn-4-en-3-one Sulfate Sodium Salt (related).
EINECS	Contact for details

Quality Control

Our Pregnenediol Sulfate Sodium is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and specific tests for related substances and residual solvents to ensure it meets stringent standards for use as a reference material. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified purity criteria, typically ≥95% to ≥98% (HPLC).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Related Substances (HPLC)	Total impurities ≤5.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.