Description

1-o-Oleoyl-2-Chloro-2-Deoxy-3-Phosphatidylcholine is a synthetic, chemically modified phospholipid analog, a key intermediate in advanced lipid research and pharmaceutical development. Its unique structure, featuring a chlorine substitution at the sn-2 position, makes it a critical building block for probing membrane biophysics and designing novel drug delivery systems. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise, reliable chemical tools for lipidomics, prodrug synthesis, and liposome formulation.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel phospholipid-based prodrugs and active pharmaceutical ingredients (APIs).
• Lipidomics & Biochemical Studies: Used as a standard or probe to investigate phospholipase activity, membrane asymmetry, and cellular signaling pathways.
• Advanced Drug Delivery Systems: A functionalized precursor for creating targeted liposomes, nanoparticles, and other nanocarriers with modified surface properties.
• Synthetic Chemistry: Serves as a specialized substrate or building block in organic synthesis for creating complex, biologically active lipid molecules.
• Diagnostic Reagent Formulation: Potential use in the development of specialized reagents for clinical diagnostics and assay kits.
• Biomimetic Material Science: Incorporated into synthetic membranes and coatings to study and mimic biological membrane properties.

Basic Information

Product Name	1-o-Oleoyl-2-Chloro-2-Deoxy-3-Phosphatidylcholine
CAS No.	131024-84-5
Molecular Formula	C44H85ClNO7P
Molecular Weight	806.57 g/mol
Synonyms	2-Chloro-2-deoxy-1-oleoyl-sn-glycero-3-phosphocholine; 1-Oleoyl-2-chloro-2-deoxy-sn-glycero-3-phosphocholine; 2-Chloro-1-oleoyl-2-deoxyphosphatidylcholine; Chlorolipid; LysoPC(18:1/Cl); 1-Oleoyl-2-chloro-lyso-phosphatidylcholine; Oleoyl Chloro LysoPC; Phosphatidylcholine, 1-o-oleoyl-2-chloro-2-deoxy-
EINECS	Contact for details

Quality Control

Our 1-o-Oleoyl-2-Chloro-2-Deoxy-3-Phosphatidylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are designed to meet the high standards of pharmaceutical and life science applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed container to reach room temperature before opening to minimize condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.