Description

8-Thiocyanatoriboflavin is a chemically modified derivative of riboflavin (Vitamin B2), where a thiocyanate group is introduced at the 8-position of the isoalloxazine ring. This structural modification is significant for creating novel biochemical probes and research tools, particularly in the study of flavin-dependent enzymes and redox processes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers engaged in advanced biochemical and photochemical research.

Application

• Biochemical Research Probe: Used as a mechanistic probe to study the active sites and electron transfer pathways of flavoproteins and flavoenzymes.
• Photochemical Studies: Serves as a model compound for investigating the photophysical and photochemical properties of modified flavins.
• Enzyme Inhibition Studies: Potential use in developing selective inhibitors for flavin-dependent enzymes for therapeutic target validation.
• Metabolic Pathway Analysis: Acts as a tracer or analog in studies related to riboflavin metabolism and utilization in biological systems.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Precursor for Specialty Chemicals: Serves as a key synthetic intermediate for the preparation of more complex, labeled, or conjugated flavin derivatives.

Basic Information

Product Name	8-Thiocyanatoriboflavin
CAS No.	130574-30-0
Molecular Formula	C17H20N4O6S
Molecular Weight	408.43 g/mol
Synonyms	8-SCN-Riboflavin; Vitamin B2 8-thiocyanate; 8-Thiocyanato-7,8-dimethyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione; Riboflavin 8-thiocyanate; 8-Thiocyano-riboflavin; 8-SCN-Flavin
EINECS	Contact for details

Quality Control

Our 8-Thiocyanatoriboflavin is produced under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to high standards suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.