Description

S(-)-Ibzm (Iodobenzamide) D2 Dopamine Receptor is a high-purity, enantiomerically pure benzamide derivative used as a selective ligand for the D2 dopamine receptor subtype. This compound is of significant value in neuroscience research and radiopharmaceutical development, particularly for positron emission tomography (PET) imaging studies. It is essential for researchers and pharmaceutical developers in the fields of neuropharmacology, molecular imaging, and central nervous system (CNS) drug discovery.

Application

• PET Imaging Tracer Development: Acts as a precursor or reference standard for radiolabeled (e.g., [123I] or [11C]) ligands used in neuroimaging.
• Neuroscience Research: Used in in vitro binding assays and autoradiography to study the distribution and density of D2 dopamine receptors in brain tissue.
• Pharmacological Profiling: Serves as a selective tool compound for characterizing the binding affinity and selectivity of new chemical entities targeting dopamine receptors.
• Reference Standard: Employed as a certified reference material (CRM) in analytical method development and validation for quality control of radiopharmaceuticals.
• Neuropsychiatric Disorder Research: Applied in studies investigating receptor alterations associated with conditions such as Parkinson's disease, schizophrenia, and addiction.

Basic Information

Product Name	S(-)-Ibzm (Iodobenzamide) D2 Dopamine Receptor
CAS No.	130383-75-4
Molecular Formula	C15H15IN2O
Molecular Weight	366.20 g/mol
Synonyms	(S)-(-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxybenzamide; (S)-(-)-Iodobenzamide; (S)-IBZM; S-(-)-IBZM; S(-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxybenzamide; S(-)-Iodobenzamide; D2 Dopamine Receptor Ligand (S)-IBZM; (S)-5-Iodo-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide
EINECS	Contact for details

Quality Control

Our S(-)-Ibzm is manufactured under strict quality control protocols to ensure high chemical and chiral purity, critical for research reproducibility. Each batch is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.