Description

Adenosine Triphosphate-1-Ethyl-3-(3-(Dimethylamino)Propyl)Carbodiimide is a specialized, water-soluble carbodiimide derivative used as a zero-length crosslinking and conjugation reagent. This compound is critical for facilitating amide bond formation between carboxylic acids and amines under mild, aqueous conditions, making it indispensable for bioconjugation strategies. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, pharmaceuticals, and diagnostics for modifying biomolecules, preparing immunoconjugates, and immobilizing proteins.

Application

• Bioconjugation and Crosslinking: For coupling peptides, proteins, antibodies, and other biomolecules to carriers, surfaces, or labels (e.g., enzymes, fluorophores).
• Immunoassay Development: Preparation of enzyme-labeled antibodies (horseradish peroxidase, alkaline phosphatase) for ELISA and other diagnostic kits.
• Affinity Chromatography: Immobilization of ligands (like proteins or antibodies) onto carboxylated matrices or beads for purification.
• Drug Delivery Systems: Conjugation of therapeutic agents to targeting molecules such as antibodies or peptides.
• Biomaterial and Surface Modification: Functionalizing polymers, nanoparticles, or sensor surfaces with bioactive molecules.
• Nucleic Acid Research: Modification of oligonucleotides with reporter groups or for surface attachment in microarray technology.
• Protein-Protein Interaction Studies: As a tool to capture and stabilize transient protein complexes for analysis.

Basic Information

Item	Detail
Product Name	Adenosine Triphosphate-1-Ethyl-3-(3-(Dimethylamino)Propyl)Carbodiimide
CAS No.	130096-08-1
Molecular Formula	C18H30N8O13P3
Molecular Weight	707.41 g/mol
Synonyms	ATP-EDC; EDC-ATP; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide Adenosine Triphosphate; Adenosine 5'-Triphosphate EDC Adduct; Carbodiimide ATP Conjugate; Water-Soluble Carbodiimide ATP; (1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide) Adenosine Triphosphate
EINECS	Contact for details

Quality Control

Our Adenosine Triphosphate-1-Ethyl-3-(3-(Dimethylamino)Propyl)Carbodiimide is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. All products undergo rigorous quality testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.